peptide ss-31 SS-31肽是一种心磷脂过氧化物酶抑制剂和线粒体靶向肽 - SS-31 peptidedosage 31 Unveiling the Potential of Peptide SS-31: A Mitochondria-Targeting Antioxidant

SS-31 peptidefor sale The field of therapeutic peptides is rapidly evolving, with peptide SS-31 emerging as a significant area of research due to its potent mitochondria-targeting capabilities and antioxidant properties. Also known by its development codes SS-31, MTP-131, and the brand name Elamipretide, this small peptide is a synthetic tetrapeptide composed of D-Arg-dimethyl-Tyr-Lys-Phe-NH2. Its unique structure allows it to accumulate within mitochondria, the powerhouses of our cells, where it exerts a range of beneficial effects.

At its core, SS-31 is a mitochondria-targeting antioxidant.作者：X Du·2024·被引用次数：41—SS-31 demonstrates remarkable efficacy in reducing elevated levels of reactive oxygen species(ROS) resulting from mitochondrial dysfunction. In Table 1, ... This means it specifically targets and protects mitochondria from damage caused by reactive oxygen species (ROS)Enhanced efficiency of mitochondria-targeted peptide SS- .... By scavenging these harmful molecules, SS-31 demonstrates remarkable efficacy in reducing elevated levels of reactive oxygen species (ROS) resulting from mitochondrial dysfunction. This protective action is crucial for maintaining cellular health and function, particularly in conditions where oxidative stress plays a significant role.

The implications of peptide SS-31's ability to improve mitochondrial function are far-reaching作者：MT Sweetwyne·2017·被引用次数：112—A short course ofSS-31 has protective benefits on glomerular mitochondria, accompanied by temporal changes to the glomerular architecture.. Research indicates that it can restore mitochondrial health, protect cells from damage, and improve energy production. This has led to its investigation as a potential therapeutic agent for a variety of age-related changes and diseases. For instance, SS-31 has been studied for its ability to restore mitochondrial health, offering hope for conditions characterized by mitochondrial decline.

One of the key mechanisms by which SS-31 operates is by acting as a cytochrome c peroxidase inhibitor and a cardiolipin peroxidation inhibitor. This action contributes to its overall role as a mitochondrion-targeted peptide. By modulating these processes, SS-31 can improve the function of mitochondria, which are vital for cellular energy metabolism. This is particularly relevant in conditions like heart failure, where mitochondrial dysfunction is a primary driver of pathology2021年1月8日—SS-31肽是一种心磷脂过氧化物酶抑制剂和线粒体靶向肽。它可以改善左心室和线粒体功能。SS-31肽可减轻人小梁网状细胞中的线粒体功能障碍和氧化损伤。. Indeed, SS-31 is a synthetic peptide that improves mitochondrial function and is currently undergoing clinical trials for treatments of heart failure.

Furthermore, studies have highlighted the protective benefits of SS-31 on specific organs and cellular structures.Application research of novel peptide mitochondrial ... For example, SS-31 has protective benefits on glomerular mitochondria, suggesting a role in kidney health. It also demonstrates the capacity to alter divalent cation (calcium) distribution within cellular membranes, potentially reducing the energetic burden associated with calcium stress.线粒体靶向抗氧化剂SS-31对脓毒症小鼠模型急性肝损伤的影响 This intricate interaction with cellular components underscores its multifaceted therapeutic potential线粒体靶向抗氧化剂SS-31肽|736992-21-5|Elamipretide.

The therapeutic applications of peptide SS-31 are being explored across a spectrum of conditions. It has shown promise in ameliorating kidney injury, with studies suggesting SS-31 is a good candidate for the treatment of AKI (Acute Kidney Injury). Its antioxidant and mitochondrial-protective effects also make it a compelling candidate for neurodegenerative diseasesThe mitochondrial-targeted peptide, SS-31, improves .... SS-31 emerges as a promising therapeutic candidate to attenuate neurodegeneration pertinent to α-synuclein misfolding and aggregation, a hallmark of conditions like Parkinson's disease.

Beyond neuroprotection, SS-31 is being investigated for its impact on metabolic disorders and genetic conditions.SS-31 (also known as Bendavia, Elamipretide, and MTP-131)is a small peptide(D-Arg- dimethyl-Tyr-Lys-Phe-NH2) that accumulates in mitochondria and ... It has been shown to reverse the mitochondrial fragmentation present in fibroblasts from patients with DCMA (a mitochondrial cardiomyopathy), suggesting SS-31 may represent a potential therapy for such conditions.作者：S Russo·2022·被引用次数：28—Our results indicate thatSS-31have beneficial effects on improving cardiac mitochondrial dysfunction in a BTHS animal model. Moreover, SS-31 is a medication used for the treatment of Barth syndrome, a rare genetic disorder affecting mitochondrial function. In this context, SS-31 peptide plays a crucial role in addressing the underlying mitochondrial defects.Dmt=2,6-dimethyl-L-tyrosine.SS-31 peptideis a cardiolipin peroxidase inhibitor and mitochondrial targeting peptide.

The research into SS-31 also extends to its effects on aging and cellular repair. It is recognized as a mitochondria-targeted peptide that supports energy, cellular repair, and anti-aging. By bolstering mitochondrial efficiency and reducing oxidative stress, SS-31 may contribute to healthier aging processes.胶原三肽_百度百科 For instance, SS-31 peptide is a mitochondria-targeted antioxidant peptide that can scavenge mitochondrial ROS, offering antioxidative effects and potentially mitigating age-related cellular damage.

In summary, peptide SS-31 represents a significant advancement in the development of targeted therapies. Its ability to accumulate in mitochondria and scavenge reactive oxygen species makes it a powerful tool for combating oxidative stress and improving mitochondrial health. From treating specific genetic disorders like Barth syndrome to offering potential solutions for heart failure, kidney injury, and neurodegenerative diseases, the research surrounding this mitochondrion-targeted peptide continues to reveal its broad therapeutic promiseElamipretide (SS-31, MTP-131) | Antioxidant Peptide. As clinical trials progress, SS-31 stands poised to play a vital role in enhancing cellular energy production, promoting repair, and potentially influencing the aging process.What is SS-31? SS-31, also known as Elamipretide,is a synthetic tetrapeptide developed to target and protect mitochondria—the.