Janoshik peptides The c-Myc peptide is a vital synthetic molecule with significant applications in molecular biology and immunology research. Derived from the human c-myc gene product, this polypeptide protein tag plays a crucial role in various experimental procedures, particularly those involving the detection and manipulation of proteins. Its ability to interact with specific antibodies makes it an indispensable tool for researchers studying cell growth, cell differentiation, and apoptosis.c-Myc Peptide
At its core, the c-Myc peptide is a short amino acid sequence that acts as an epitope, a specific region on a molecule that is recognized by an antibody.c-Myc Peptide The most commonly utilized sequence for the c-Myc tag peptide is EQKLISEEDL, which corresponds to amino acids 410-419 of the C-terminal of the human c-myc protein. This specific sequence is recognized by anti-c-Myc antibodies, such as the widely used 9E10 antibody. The c-Myc is a helix-loop-helix leucine zipper phosphoprotein that regulates gene transcription, and its dysregulation is implicated in a significant percentage of cancersMyc-Tag - an overview. Indeed, c-Myc is an oncogene that is dysregulated in ~70% of cancers, highlighting its importance in disease pathology.
One of the primary applications of the c-Myc peptide is in immunoassays. It is useful for displacement of c-Myc-tagged fusion proteins bound to anti-c-Myc antibodies. In essence, when a protein of interest is engineered to include the c-Myc tag (a technique often referred to as protein modification), researchers can use antibodies to isolate or detect this tagged protein. However, sometimes it's necessary to release the bound protein from the antibodyTargeting c-Myc with a novel Peptide Nuclear Delivery .... This is where the c-Myc peptide proves invaluable. By adding a high concentration of the free c-Myc peptide to the system, it can competitively bind to the anti-c-Myc antibodies, effectively displacing the c-Myc-tagged fusion proteins. This process is crucial for various purification and analysis techniques. For instance, Thermo Scientific Pierce Anti-c-Myc Agarose is a resin that utilizes anti-c-Myc antibodies to purify recombinant c-Myc-tagged proteins. The c-Myc Peptide can then be used to elute these purified proteins from the resin145646-22-6・c-Myc Peptide・133-19211[Detail Information].
Beyond its role in displacement, the c-Myc peptide also serves as a critical component in blocking experiments.作者:D Guneri·2025—c-Myc is an oncogene that is dysregulated in ∼70% of cancers. Its multifaceted function complicates effective drug targeting of the protein. i-Motif (iM) DNA ... When researchers want to confirm that an observed effect is specifically due to the c-Myc tag and not some other interaction, they can use the c-Myc peptide to block the antibody binding sitec-Myc Peptide TFA | Growth Regulated Agent. This ensures that any subsequent antibody binding or downstream effects are indeed related to the target protein. This is why c-Myc Tag peptides are substitutes for c-Myc fusion proteins in certain experimental setups, allowing for controlled competition and validation.
The c-myc gene product itself, c-Myc, encodes a nuclear phosphoprotein that plays a critical role in regulating fundamental cellular processes. Its involvement extends to cell cycle progression, proliferation, differentiation, and apoptosis. Aberrant expression of c-Myc is strongly linked to the development and progression of various cancers, including B-cell lymphomas and lung cancer. Therefore, understanding and manipulating c-Myc pathways is a significant area of cancer research.c-Myc Peptide (TFA) is a synthetic peptide corresponding to the C-terminal amino acids (410-419) of human c-myc protein, and participates in regulation of ... The c-Myc peptide provides a convenient way to study these interactions without needing to work with the full-length protein, which can be more challenging to handle and express.
The c-Myc peptide tag is a versatile tool, and its applications extend to various research areas. For example, it can be used in systems for protein purification and characterization. The c-Myc tag is a 10-residue peptide sequence that simplifies the labeling and detection of proteins, making it easier to study protein interactions and cellular localization.Thec-Myc Peptideis a synthetic peptide with an amino acid sequence that corresponds to the amino acids 410-419 of theC-terminal of humanc-myc. Researchers can also find Human c-Myc peptide for specific studiesThis gene is a proto-oncogene andencodes a nuclear phosphoproteinthat plays a role in cell cycle progression, apoptosis and cellular transformation.. The availability of various forms, such as c-Myc Peptide (TFA), offers flexibility for different experimental conditions. The availability of Pierce c-Myc Peptide and other commercial options from suppliers like GenScript peptides and BioLegend ensures that researchers have access to high-quality reagents for their work.
In summary, the c-Myc peptide is a fundamental reagent in biological researchHuman c-Myc peptide (ab166837). Its specific amino acid sequence, derived from the c-myc gene product, allows it to be recognized by anti-c-Myc antibodies.c-Myc Peptide Tag (Previously Covance catalog# PEP-150P) This interaction is leveraged for protein purification, displacement assays, and blocking experiments, all crucial for understanding the complex roles of c-Myc in cellular processes and its implications in diseases like cancerc-Myc tag peptide(EQKLISEEDL). Availability (in Japan). 10 or more. (In Japan at 00:05, Jan 28, 2026 in JST .... The c-Myc is a key regulator of cell growth, and tools like the c-Myc peptide are essential for unraveling its intricate functions.145646-22-6・c-Myc Peptide・133-19211[Detail Information]
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